概要：The patient presented with bilateral tumors, not responding to the SIOP-2001 pre-surgery chemotherapy (4 weeks of Act D and VCR), the tumors were removed by kidney sparing surgery.
In the following year without cytotoxic treatment, the patient again developed bilateal tumors.
Cell culture was established from the left tumor which showed fetal rhabdomyomatous histology as described by Royer-Pokora 2010.
Receptors Expressed：Receptor tyrosine kinases EGFR, EphA7, PDGFRalpha, FGFR1, PDGFRbeta, AxL
Tumorigenic：Yes, in nude mice. Forms tumor with small cells consistent with Wilms tumor (xenografts may not represent Wilm?s tumors completely, see E. Kunce Stroup 2017)
