概要：The WT-CLS1 cell line was established from a primary Wilms? tumor by CLS in 1998.
However, the cells have rhabdoid characteristics, as demonstrated by E.
Kunce Stroup et al.
in 2017.
WT-CLS1 cells are sensitive to miR-16, as a result cyclin D genes expression decreases.
In addition, the cells showed a unique resistance to IGF1R inhibition, in contrast to true Wilm?s tumor cells.
仕様
容量：1vial
カテゴリー：Kidney cancer cell lines
Organism：Human
Tissue：Kidney
Disease：Rhabdoid tumor
Synonyms：CLS1
Age：5 years
Gender：Female
Ethnicity：Caucasian
Morphology：Epithelial-like
Cell Type：B lymphoblast
Growth Properties：Monolayer, adherent
Citation：WT-CLS1 (Cytion catalog number 300379)
Biosafety Level：1
Tumorigenic：Yes, in nude mice. Forms tumor with small cells consistent with Wilms tumor (xenografts may not represent Wilm?s tumors completely, see E. Kunce Stroup 2017)
