概要:The imWilms10T cell line was immortalized from Wilms10 cells, a primary tumor cell line which was established in 2015 by the group of Dr.
Brigitte Royer-Pokora from tissue of a 2-year-old female patient with triphasic stromal predominant Wilms tumor.
Immortalization using the catalytic subunit of human telomerase 8hTERT) in conjunction with the mutant (U19dl89-97tsA58) SV40 large T antigen (LT) resulted in the cytogenetically stable cell line imWilms10.
仕様
容量:1vial
カテゴリー:Kidney cancer cell lines
Organism:Human
Tissue:Kidney
Disease:Wilms Tumor
Synonyms:ImWilms10 T, IM-WT-10
Age:2 years
Gender:Female
Ethnicity:Caucasian
Morphology:Spindle-shaped
Cell Type:Wilms cells
Growth Properties:Adherent
Citation:ImWilms10T (Cytion catalog number 300419)
Biosafety Level:1
Mutational Profile:WT1 mutation status: homozygous del WT1 within del11p13, LOH: no in 11p13 but UPD in 11p15, CTNNB1 mutation status: homozygous del TCT, p.DS45, UPD 3p