概要:The CX-1 cell line is a unique subclone derived from the HT-29 cell line, which is known for its remarkable properties.
CX-1 cells, derived from the human colon xenograft model xC-1, were generated by introducing HT-29 cells into athymic mice.
They are of the same origin as HT-29, female and have an age of 44 years at harvest.
CX-1 cells play an important role in the study of adenocarcinoma of the colon and serve as a reliable model system for studying the intricacies of this disease at the cellular level.
These cells have a fast doubling time of about 24 hours, ensuring greater efficiency of experimental procedures and accelerating research results.
The TP53 mutation (p.Arg273His) was observed, which has a nucleotide substitution from G to A (CGT to CAT) and leads to a mutation effect from arginine to histidine.
In addition, the P53 protein was detected in CX-1 cells by immunoblotting.