Products:Carcinoembryonic antigen (CEA), 600 ng/ml per 10 exp6 cells per 10 days, keratin
Mutational Profile:T84 cells carry a heterozygous Kras mutation in codon13: GGC(Wt Gly) |BiggerAs|GAC(Asp)
Karyotype:The stemline modal chromosome number is 56, occurring at 28% with polyploidy at 12.4%. Eighteen markers are common to most metaphases examined. Normal x and chromosome 13 were absent, chromosomes 2, 4 and 22 were single-copied, and chromosome 12 was 4-copied.No Y chromosome was detected by Q band observation. DM occurred in nearly 50% of the cells.