83-5596-47 WiDr Cells 1vial 300377
特徴
- 概要:According to Chen TR, 1987, the WiDr cell line is a derivative of the HT-29 cell line.
- The cells are negative for Colon Antigen 3 expression, but positive for keratin by immunoperoxidase staining.
- The cells expressed p53 antigen (the p53 produced has a G -|BiggerAs| A mutation resulting in Arg -|BiggerAs| His at position 273).
- Growth of WiDr cells is inhibited by tumor necrosis factor alpha (TNF Inhibitors of dihydrofolate reductase are highly cytotoxic to WiDr cells).
仕様
- 容量:1vial
- カテゴリー:Intestine cancer cell lines
- Organism:Human
- Tissue:Colon
- Disease:Adenocarcinoma
- Synonyms:WiDR, WIDR, WiDr/S, WiDr-TC, WiDrTC, LED-WiDr, Led-WiDr
- Age:44 years
- Gender:Female
- Morphology:Epithelial-like
- Growth Properties:Adherent
- Citation:WiDr (Cytion catalog number 300377)
- Biosafety Level:1
- Receptors Expressed:Epidermal growth factor (EGF)
- Protein Expression:CEA positive
- Antigen Expression:HLA A24, A32, B15, B18
- Isoenzymes:PGM1, 1-2, PGM3, 1-2, G6PD, B, ES-D, 1, PEP-D, 1, 6PGD, A
- Tumorigenic:Yes, in nude mice
- Products:Carcinoembryonic antigen (CEA) 118 ng/106 cells/10 days, Colon Specific Antigen (CSAp), transforming growth factor beta, keratin
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