概要：The 8305C cell line is derived from a 67-year-old womans primary undifferentiated thyroid carcinoma.
These cells offer a reliable model for studying gene mutations in malignant transformation.
With a doubling time of approximately 55-60 hours, they provide an efficient system for research.
The 8305C cells exhibit characteristics of undifferentiated thyroid carcinomas, including residual well-differentiated components.
They carry a mutation in the p53 gene, which is associated with undifferentiated carcinoma.
Researchers can utilize these cells to explore the molecular mechanisms underlying thyroid carcinoma progression and develop targeted therapies for this aggressive cancer.
