概要:Established from an 11-year-old boy with Burkitt lymphoma.
This cell line is a variant of Burkitt cell line Raji.
This cell line is deficient in expression of HLA Class II antigen.
RJ2.2.5 is deleted at least in 1 allele of the MHC Class II transactivator (CIITA), the other allele of CIITA is also affected but not completely deleted.
RJ2.2.5 is EBNA positive of Epstein Barr virus.
仕様
容量:1vial
カテゴリー:Burkitt Lymphoma cell lines
Organism:Human
Tissue:Hematopoietic
Disease:Burkitt lymphoma
Applications:Analysis of B cell surface antigens, testing of cytotoxic drugs, mutational analysis, analysis of apoptotic mechanisms, HLA-typing