特徴
- 概要:Established 1967 from a 16-year-old African boy with Burkitt?s Lymphoma.
- Daudi is reported to be EBV-positive.
- The cell line is deficient of HLA-ABC expression on the cell surface due to the absence of beta-2-microglobulin, responsible for correct intracellular folding and processing of the MHC class I molecule in the endoplasmic reticulum.
仕様
- 容量:1vial
- カテゴリー:Burkitt Lymphoma cell lines
- Organism:Human
- Tissue:Blood
- Disease:Burkitt lymphoma
- Applications:Analysis of B cell surface antigens, testing of cytotoxic drugs, mutational analysis, analysis of apoptotic mechanisms, assay development.
- Synonyms:DAUDI, NK-10A, NK-10a, NK 10a, NK10a, N, GM03190, GM3190, GM03190A, GM17346
- Age:16 years
- Gender:Male
- Ethnicity:African
- Morphology:Round cells
- Cell Type:B lymphoblast
- Growth Properties:Suspension
- Citation:Daudi (Cytion catalog number 302009)
- Biosafety Level:Daudi cells do not release Epstein-Barr virus (EBV) when cultured, classifying them as Risk Group 1. However, when used for genetic experiments, they should be treated as Risk Group 2 cells.
- Antigen Expression:CD10+, CD19+, CD20+, CD21+, CD22+, CD23-, CD24-, CD32+, CD37+, CD38+, CD39-,CD40+, CD54+, CD72+, CD73-, CD75+, CD77+, CD81+, CD82+, CD83-, CD84+, CD86+
- Karyotype:46, almost diploid
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