Barr in 1963 from biopsy fragments and cell clumps of a lymphoma.
These were seeded into Insulin bottles in Eagles basal medium with 10% human serum and fed by medium addition.
The cells grew as free-floating singel individuals or doublets with a mean doubling time of about 48 hours and were identified as altered lymphoblasts on the basis of growth and uniform morphology.
仕様
容量:1vial
カテゴリー:Burkitt Lymphoma cell lines
Organism:Human
Tissue:Blood
Disease:Burkitt lymphoma
Synonyms:EB-1, Epstein-Barr-1
Age:9 years
Gender:Female
Ethnicity:African
Morphology:Polymorph cells, big nuclei, formation of microvilli
Cell Type:B lymphocyte
Growth Properties:Suspension
Citation:EB1 (Cytion catalog number 300403)
Biosafety Level:1
Isoenzymes:PGM1, ESD1, GLO-1, G6PD, B
Viruses:Contains Herpesvirus
Karyotype:Chromosome Frequency Distribution 30 cells: 2n = 46. The cell line is aneuploid human female, with chromosome counts in the near dipoidrange. Normal chromosomes N8, N11 and N14 are monosomic, with the remainder of autosomes usually being paired. The x chromosome most often is trisomic. Four marker chromosomes are found. Two of these (markers M1 and M3) involve the reciprocal translocation between chromosomes N8 and N14 associated with most Burkitts lymphoma cell lines.