Kitamura in October 1987 from a heparinised bone marrow aspiration sample from an erytholeukemic patient.
TF-1 cells proliferate depending on the GM-CSF and IL-3.
The morphological and cytochemical features, plus the constitutive expression of globin genes, indicate the commitment of the cells to the erythroid lineage.
TPA induces a dramatic differentiation into macrophage-like cells.
仕様
容量:1vial
カテゴリー: Leukemia cell lines
Organism:Human
Tissue:Bone marrow
Disease:Erythroleukemia
Applications:The TF-1 cell line can be applied in various systems due to their responsiveness to multiple cytokines. They provide a good system to investigate the proliferation and differentiation of myeloid progenitor cells. Sensitive to GM-CSF, IL-3, EPO.
Synonyms:TF1, MFD-1
Age:35 years
Gender:Male
Ethnicity:Japanese
Growth Properties:Suspension
Citation:TF-1 (Cytion catalog number 300434)
Biosafety Level:1
Receptors Expressed:TF-1 cells do not express glycophorin A or carbonyl anhydrase I.