83-5593-87　U87MG Cells 1vial　300367

特徴

• 概要：U87MG, also known as U87 cells, is a well-known cell line in biological research.
• U87MG stands for Uppsala 87 Malignant Glioma.
• This cell line was originally obtained from a 44-year-old male patient in 1966 at Uppsala University.
• While the commercially available U87MG cell line is believed to be of CNS origin and likely a human glioblastoma cell line, its exact origin is unknown.
• The genetics of this cell line has been compared to the original tumor from which it was derived and found to differ, highlighting the importance of validating cell lines used in research.
• These cells have epithelial morphology and are widely used in neuroscience and immuno-oncology research in the study of gliomas.
• U87MG cells have a doubling time of approximately 18 to 38 hours and are 12 to 14 micrometer in size.
• In terms of growth conditions, these cells should be cultured in a loose, attached cluster formation and fed with fresh medium every 2 to 3 days.
• The culture should be allowed to incubate undisturbed until day 3 for best attachment, and the dislodged or floating cells should be added back to the adherent population.
• These cells have a diploid karyotype with 2n = 46.
• When it comes to researching glioblastoma, a variety of cell lines are used, including human-derived cell lines such as U251 and U87, murine cell line GL261, and rat cell lines such as 9L/LacZ, F98, RG2, CNS-1, and C6.