Tumorigenic:Yes, in nude mice and also in hamster cheek
Karyotype:Hypodiploidy to pseudodiploidy. Abnormalities including double minutes, breaks, large submetacentric, telocentric and small telocentric markers (originator). (P32) Hypodiploid to hyperdiploid and triploid to hypotetraploid with abnormalities including dicentrics, breaks, double minutes (DM), large subtelocentric and small telocentric chromosomes.