83-3904-45 [取扱停止]PE-Labeled Monoclonal Anti-G4S linker Antibody, Mouse IgG1 (AM635) 25tests G4S-PFM635-25tests
特徴
- 背景
- The poly-Glycine-Serine (G4S) linker is a type of flexible, unstructured synthetic peptide linker sequence often leveraged to connect the variable heavy (VH) domain and variable light (VL) domain of single-chain variable fragments (scFvs) and chimeric antigen receptors (CARs) that utilize an extracellular domain scFv for target antigen recognition.
- The linker itself consists of a core pentapeptide sequence, Gly-Gly-Gly-Gly-Ser, that is repeated and commonly found as either a 15-mer (G4S)3 or20-mer(G4S) 4 within scFv-based CARs and scFv fragments.
- The linker sequence length plays a role in controlling scFv stability and the noncovalent association between the VH and VL domains.
仕様
- 容量:25tests
- Source:Monoclonal Anti-G4S linker Antibody, Mouse IgG1 (AM635) is a mouse monoclonal antibody recombinantly expressed from human 293 cells (HEK293).
- Species Reactivity:Mouse
- Host:HEK293
- Tag:Mouse IgG1 | Mouse Kappa
- Molecule:G4Slinker
- Format:Powder
- Conjugate:PE Labeled
- Endotoxin:1.0 EU per μg
- Buffer:PBS, pH7.4
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商品のバリエーション (サイズ違い・スペック違い・オプション品など)
| 商品イメージ | アズワン品番 商品名 |
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83-3904-44
PE-Labeled Monoclonal Anti-G4S linker Antibody, Mouse IgG1 (AM635) 200tests
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83-3904-45
PE-Labeled Monoclonal Anti-G4S linker Antibody, Mouse IgG1 (AM635) 25tests
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