83-3903-41 Biotinylated Anti-Human CD3 Antibody, Mouse IgG2a,Avitag （Clone： OKT3）, premium grade 50ug CDE-BV84G0-50ug
特徴
- 背景
- CD3e molecule, epsilon is also known as CD3E, is a T-cell surface single-pass type I membrane glycoprotein.
- CD3E contains 1 Ig-like （immunoglobulin-like） domain and 1 ITAM domain.
- CD3E, together with CD3-gamma, CD3-delta and CD3-zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T cell receptor-CD3 complex.
- This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways.
- The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11.
- The epsilon polypeptide plays an essential role in T-cell development.
- CD3E plays an essential role in T-cell development, and defects in CD3E gene cause severe immunodeficiency.
- CD3E gene has also been linked to a susceptibility to type I diabetes in women.
- CD3E has been shown to interact with TOP2B, CD3EAP and NCK2.
仕様
- 容量：50ug
- Source：Biotinylated Anti-Human CD3 Antibody, Mouse IgG2a,Avitag （Clone： OKT3）, premium grade is a chimeric monoclonal antibody recombinantly expressed from human 293 cells （HEK293）, which combines the variable region of a mouse monoclonal antibody. The mouse monoclonal antibody is produced from a hybridoma resulting from fusion of SP2/0 myeloma and B-lymphocytes obtained from a mouse immunized with CD3 epsilon.
- Species Reactivity：Mouse
- Host：HEK293
- Tag：Mouse IgG2a ＆ Avi | Mouse kappa
- Molecule：CD3
- Format：Liquid
- Conjugate：Biotin-labeled
- Endotoxin：0.002 EU per μg
- Purity：95％
- Buffer：PBS, pH7.4
- この商品は法規制を確認しておりません。（法規制によって販売できない場合もございます）
- 【試薬に関するお問合せ】
- アズワン株式会社 試薬・プロセス材料グループ
- TEL：06-6447-8641
- FAX：06-6447-8642
- E-mail：[email protected]
商品のバリエーション （サイズ違い・スペック違い・オプション品など）
よくあるご質問（FAQ）
掲載カタログ情報
| 掲載カタログ名 | 掲載ページ |
|---|