83-3900-87　［取扱停止］Anti-SARS-CoV-2 Spike RBD Neutralizing Antibody, Human IgG1 （AS35） 1mg　SAD-S35-1mg

特徴

• 背景
• It's been reported that Coronavirus can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor.
• The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2.
• S1 mainly contains a receptor binding domain （RBD）, which is responsible for recognizing the cell surface receptor.
• S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.

仕様

• 容量：1mg
• Source：Anti-SARS-CoV-2 Spike RBD Neutralizing Antibody, Human IgG1 （AS35） （SAD-S35） is isolated from a SARS-CoV-2 infected patient and is recombinantly produced from human 293 cells （HEK293）. This antibody recognizes the SARS-CoV-2 Spike Protein RBD domain and inhibits the interaction between SARS-CoV-2 RBD and ACE2 with an IC50 of 1.47 μg/mL using SARS-CoV-2 Inhibitor Screening Kit.＜strong＞Pseudovirus assay shows that this antibody has potent neutralizing activity against pseudovirus bearing SARS-CoV-2 Spike protein.＜/strong＞
• Species Reactivity：Human
• Host：HEK293
• Tag：Human IgG1 | Kappa
• Application：ELISA
• Molecule：Spike RBD
• Format：Powder
• Conjugate：Unconjugated
• Purity：95％
• Buffer：PBS, pH7.4
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