Kallikrein-3 (KLK3) is also known as Prostate-specific antigen (PSA), APS, Gamma-seminoprotein (Seminin), P-30 antigen, Semenogelase, is a glycoprotein enzyme, is a member of the kallikrein-related peptidase family and is secreted by the epithelial cells of the prostate gland.
The preferential cleavage site of KLK3 is “-Tyr-|-Xaa-“, the catalytic activity is inhibited by SERPINA5 and is strongly inhibited by Zn2+.
KLK3 hydrolyzes semenogelin-1 thus leading to the liquefaction of the seminal coagulum.
特徴
This protein carries a polyhistidine tag at the C-terminus.
The protein has a calculated MW of 28.7 kDa.
The protein migrates as 33-36 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
仕様
容量：1mg
Source：Human Kallikrein 3 Protein, His Tag (KL3-H52H3) is expressed from human 293 cells (HEK293).
Species Reactivity：Human
Host：HEK293
Tag：C-10×His
Format：Powder
Conjugate：Unconjugated
Swiss-Prot：P07288-1
Endotoxin：1.0 EU per μg
Purity：95%
Buffer：50 mM Tris, 150 mM NaCl, 0.05% Brij-35, pH7.5
