83-3899-25　Biotinylated Human HLA-DRA1*01：01＆HLA-DRB1*11：01＆Influenza HA （PKYVKQNTLKLAT） Complex Protein （Monomer） 25ug　HLA-H82E7-25ug

特徴

• 背景
• Neuraminidase (NA) and hemagglutinin (HA) are major membrane glycoproteins found on the surface of influenza virus.
• Hemagglutinin binds to the sialic acid-containing receptors on the surface of host cells during initial infection and at the end of an infectious cycle.
• Hemagglutinin also plays a major role in the determination of host range restriction and virulence.
• As a class I viral fusion protein, hemagglutinin is responsible for penetration of the virus into the cell cytoplasm by mediating the fusion of the membrane of the endocytosed virus particle with the endosomal membrane.
• The Human HLA-DRA1*0101 & HLA-DRB1*1101 Influenza HA (PKYVKQNTLKLAT) complex protein is a complex of HLA-DRA1*0101 & HLA-DRB1*1101 of the MHC Class II and PKYVKQNTLKLAT peptide of the Influenza HA.
• 特徴
• Biotinylated Human HLA-DRA1*01:01&HLA-DRB1*11:01&Influenza HA (PKYVKQNTLKLAT) Complex Protein is produced by co-expression of HLA-DRA1 and HLA-DRB1 loaded with Influenza HA peptide.This protein carries a polyhistidine tag at the C-terminus, followed by an Avi tag (Avitag).The protein has a calculated MW of 29.2 kDa and 29.2 kDa.
• The protein migrates as 38-42 kDa and 35-36 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.