Survivin, also known as BIRC5 and EPR-1, is a member of the inhibitor of apoptosis (IAP) family, which encodes negative regulatory proteins that prevent apoptotic cell death.
IAP family members usually contain multiple baculovirus IAP repeat (BIR) domains, but birc5 encodes proteins with only a single BIR domain.
The Human HLA-A*0201 Survivin (TLPPAWQPFL) complex protein is a complex of HLA-A*0201 of the MHC Class I, B2M and TLPPAWQPFL peptide of the Survivin.
特徴
Biotinylated Human HLA-A*02:01&B2M&Survivin (TLPPAWQPFL) Complex Protein is produced by co-expression of HLA and B2M loaded with Survivin peptide.This protein carries a polyhistidine tag at the C-terminus, followed by an Avi tag (Avitag).The protein has a calculated MW of 36.3 kDa and 13.9 kDa.
The protein migrates as 40-43 kDa and 12 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
仕様
容量：25ug
Source：Biotinylated Human HLA-A*02:01&B2M&Survivin (TLPPAWQPFL) Complex Protein (HLN-H82E5) is expressed from human 293 cells (HEK293). It contains AA Gly 25 - Ile 308 (HLA-A*02:01) & Ile 21 - Met 119 (B2M) & TLPPAWQPFL peptide (Accession # AAA59606.1 (HLA-A*02:01) & P61769-1 (B2M) & TLPPAWQPFL).
Species Reactivity：Human
Host：HEK293
Tag：C-10×His & C-Avi
Exp Region：Gly 25 - Ile 308 (HLA-A*02:01) & Ile 21 - Met 119 (B2M) & TLPPAWQPFL peptide
