Interleukin-3 (IL-3) is an interleukin, a type of biological signal (cytokine) which is encoded by the IL-3 gene located on chromosome 5 and produced primarily by activated T cells beside human thymic epithelial cells, activated murine mast cells, murine keratinocytes and neurons/astrocytes.
The protein acts in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages.
The human IL-3 reported to be a monomer, as it is known, contains 133 amino acids residues which is a single non-glycosylated polypeptide.
Specifically, human and murine IL-3 share low homology and it does not show activity on murine cells.
特徴
This protein carries no "tag".
The protein has a calculated MW of 15.1 kDa.
The protein migrates as 14 kDa±3 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE).
仕様
容量：50ug
Source：Human IL-3 Protein, premium grade (IL3-H5115) is expressed from E. coli cells. It contains AA Ala 20 - Phe 152 (Accession # P08700-1).
