Human PVRIG (poliovirus receptor related immunoglobulin domain-containing protein), also known as CD112 receptor (CD112R), is an approximately 34 kDa single transmembrane protein in the poliovirus receptor-like protein (PVR) family.
The CD112R gene encodes a putative single transmembrane protein, which is composed of a single extracellular IgV domain, one transmembrane domain, and a long intracellular domain.
Notably, the intracellular domain of phatases.
The extracellular domain sequence of human and mouse CD112R have 65.3% similarity.
CD112R may act as a coinhibitory receptor that suppresses T-cell receptor-mediated signals.
特徴
This protein carries a human IgG1 Fc tag at the C-terminus, followed by an Avi tag (Avitag).
The protein has a calculated MW of 42.3 kDa.
The protein migrates as 53-60 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
仕様
容量：200ug
Source：Biotinylated Mouse PVRIG Protein, Fc,Avitag (PVG-M82F3) is expressed from human 293 cells (HEK293). It contains AA Ser 35 - Asp 165 (Accession # A0A1B0GS01-1).
Species Reactivity：Mouse
Host：HEK293
Tag：C-Fc & C-Avi
Exp Region：Ser 35 - Asp 165
Format：Powder
Conjugate：Biotin-labeled
Swiss-Prot：A0A1B0GS01-1
Endotoxin：1.0 EU per μg
Purity：90%
Buffer：50 mM Tris, 100 mM Glycine, 25 mM Arginine, 150 mM NaCl, pH7.5
