This gene encodes a member of the mannose receptor family of proteins that contain a fibronectin type II domain and multiple C-type lectin-like domains.
The encoded protein plays a role in extracellular matrix remodeling by mediating the internalization and lysosomal degradation of collagen ligands.
Expression of this gene may play a role in the tumorigenesis and metastasis of several malignancies including breast cancer, gliomas and metastatic bone disease.
特徴
This protein carries a polyhistidine tag at the C-terminus.
The protein has a calculated MW of 158.0 kDa.
The protein migrates as 170-180 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
仕様
容量：1mg
Source：Human MRC2 Protein, His Tag (MR2-H52H3) is expressed from human 293 cells (HEK293). It contains AA Gly 31 - Ala 1414 (Accession # Q9UBG0).
