Neuraminidase (NA) and hemagglutinin (HA) are major membrane glycoproteins found on the surface of influenza virus.
Hemagglutinin binds to the sialic acid-containing receptors on the surface of host cells during initial infection and at the end of an infectious cycle.
Neuraminidase, on the other hand, cleaves the HA-sialic acid bondage from the newly formed virions and the host cell receptors during budding.
Neuraminidase thus is described as a receptor-destroying enzyme which facilitates virus release and efficient spread of the progeny virus from cell to cell.
特徴
This protein carries a polyhistidine tag at the N-terminus.
The protein has a calculated MW of 45.0 kDa.
The protein migrates as 55-65 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
仕様
容量：1mg
Source：Influenza A (A/Sydney/1304/2022) Neuraminidase (NA) Protein, His Tag (NE2-V5247) is expressed from human 293 cells (HEK293). It contains AA Lys 80- Thr 469 (Accession # EPI2304606, GISAID).
