Neuraminidase (NA) and hemagglutinin (HA) are major membrane glycoproteins found on the surface of influenza virus.
Hemagglutinin binds to the sialic acid-containing receptors on the surface of host cells during initial infection and at the end of an infectious cycle.
Neuraminidase, on the other hand, cleaves the HA-sialic acid bondage from the newly formed virions and the host cell receptors during budding.
Neuraminidase thus is described as a receptor-destroying enzyme which facilitates virus release and efficient spread of the progeny virus from cell to cell.
特徴
This protein carries a polyhistidine tag at the N-terminus.
The protein has a calculated MW of 44.9 kDa.
The protein migrates as 52-55 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
仕様
容量：100ug
Source：Influenza A (A/Georgia/12/2022 CVR-167) Neuraminidase (NA) (A/pdm09 linage) Protein, His Tag (NEE-V524p) is expressed from human 293 cells (HEK293). It contains AA Val 80- Asn 469 (Accession # EPI2756234, GISAID).
