The protein encoded by this gene is a type I membrane protein that forms one of the two chains of a receptor for interferons alpha and beta.
Binding and activation of the receptor stimulates Janus protein kinases, which in turn phosphorylate several proteins, including STAT1 and STAT2.
The protein belongs to the type II cytokine receptor family and functions as an antiviral factor.
特徴
This protein carries a polyhistidine tag at the C-terminus.
The protein has a calculated MW of 49.3 kDa.
The protein migrates as 65-95 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
仕様
容量：1mg
Source：Cynomolgus IFN-alpha/beta R1 Protein, His Tag (IF1-C52H3) is expressed from human 293 cells (HEK293). It contains AA Ala 25 - Lys 437 (Accession # A0A7N9D7J0-1).
