Tumor necrosis factor receptor superfamily member 25 (TNFRSF25) is also known as Apo-3, Death receptor 3 (DDR3 or DR3), Apoptosis-inducing receptor AIR, Apoptosis-mediating receptor TRAMP, Lymphocyte-associated receptor of death, Apo-3, which is a member of the TNF-receptor superfamily.
TNFRSF25 is a homodimer protein, which can Interact strongly via the death domains with TNFRSF1 and TRADD to activate at least two distinct signaling cascades, apoptosis and NF-kappa-B signaling.
TNFRSF25 is receptor for TNFSF12 / APO3L / TWEAK.
特徴
This protein carries a human IgG1 Fc tag at the C-terminus.
The protein has a calculated MW of 45.5 kDa.
The protein migrates as 53-63 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
仕様
容量：100ug
Source：Human DR3 Protein, Fc Tag (DR3-H5253) is expressed from human 293 cells (HEK293). It contains AA Gln 25 - Gln 199 (Accession # Q93038-1).
Species Reactivity：Human
Host：HEK293
Tag：C-Fc
Exp Region：Gln 25 - Gln 199
Format：Powder
Conjugate：Unconjugated
Swiss-Prot：Q93038-1
Endotoxin：1.0 EU per μg
Purity：90%
Buffer：50 mM Tris, 100 mM Glycine, 25 mM Arginine, 150 mM NaCl, pH7.5
