Six-transmembrane epithelial antigen of the prostate 1 (STEAP1) is an integral membrane protein that is highly up-regulated on the cell surface of several human cancers, making it a promising therapeutic target to manage these diseases.
It shares sequence homology with three enzymes (STEAP2-STEAP4) that catalyze the NADPH-dependent reduction of iron(III).
Taking into account its high specificity and overexpression in human cancers, STEAP1 is nowadays a promising candidate to be imposed as a therapeutic target.
特徴
This protein carries a twin strep tag at the N-terminus and a polyhistidine tag at the C-terminus.
The protein has a calculated MW of 44.7 kDa.
The protein migrates as 38 kDa, 65 kDa and 95 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
仕様
容量：20ug
Source：Human STEAP1 Full Length Protein, Twin-Strep,His Tag (ST1-H5283) is expressed from human 293 cells (HEK293). It contains AA Glu 2 - Leu 339 (Accession # Q9UHE8-1).
