The heterodimer glycoprotein H-glycoprotein L is required for the fusion of viral and plasma membranes leading to virus entry into the host cell.
Acts as a functional inhibitor of gH and maintains gH in an inhibited form.
Upon binding to host integrins, gL dissociates from gH leading to activation of the viral fusion glycoproteins gB and gH.
特徴
This protein carries a twin strep tag at the C-terminus.
The protein has a calculated MW of 90.2 kDa & 17 kDa.
The protein migrates as 110-130 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
仕様
容量：500ug
Source：Varicella zoster virus (strain Oka vaccine) gH&gL Protein, Twin-Strep Tag&His Tag (GHL-V5283) is expressed from human 293 cells (HEK293). It contains AA Asn 18-Arg 795 & Leu 23 - Gln 160 (Accession # Q775J3 & Q9J3N1).
