The protein encoded by this gene is a receptor for interleukin 7 (IL7).
The function of this receptor requires the interleukin 2 receptor, gamma chain (IL2RG), which is a common gamma chain shared by the receptors of various cytokines, including interleukins 2, 4, 7, 9, and 15.
This protein has been shown to play a critical role in V(D)J recombination during lymphocyte development.
Defects in this gene may be associated with severe combined immunodeficiency (SCID).
Alternatively spliced transcript variants have been found.
特徴
Biotinylated Human IL-7 R alpha & IL-2 R gamma Protein has a calculated MW of 32.2 kDa (IL-7 R alpha) & 31.2 kDa (IL-2 R gamma).
The protein migrates as 43-65 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
仕様
容量：100ug
Source：Biotinylated Human IL-7 R alpha & IL-2 R gamma Protein, His,Avitag&Tag Free (ILA-H82W3) is expressed from human 293 cells (HEK293). It contains AA Glu 21 - Asp 239 & Leu 23 - Asn 254 (Accession # P16871-1 & P31785-1).
