Cadherin-17, also known as liver-intestine (LI) Cadherin, belongs to the cadherin family of calcium-dependent cell adhesion molecules.
In vivo studies showed CDH17 knockout resulted in apoptotic PC tumor death through activating caspase-3 activity.
Taken together, CDH17 functions as an oncogenic molecule critical to PC growth by regulating tumor apoptosis signaling pathways and CDH17 could be targeted to develop an anti-PC therapeutic approach.
特徴
This protein carries a human IgG1 Fc tag at the C-terminus, followed by an Avi tag (Avitag).
The protein has a calculated MW of 112.4 kDa.
The protein migrates as 130-150 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
仕様
容量：200ug
Source：Biotinylated Mouse Cadherin-17 Protein, Fc,Avitag (CA7-M82F3) is expressed from human 293 cells (HEK293). It contains AA Phe 26 - Met 786 (Accession # Q9R100-1).
