Matrix metalloproteinase-8（MMP-8）also known as neutrophil collagenase and CLG1，is a member of matrix metalloproteinases (MMPs) family，which degrade components of the extracellular matrix (ECM) and play essential roles in various physiological processes as well as pathological processes.
MMP-8 may affect the metastatic behavior of breast cancer cells through protection against lymph node metastasis, underlining the importance of anti-target identification in drug development.
MMP-8 in the tumor may have a protective effect against lymph node metastasis.
特徴
This protein carries a polyhistidine tag at the C-terminus.
The protein has a calculated MW of 28.9 kDa.
The protein migrates as 35-40 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
仕様
容量：1mg
Source：Mouse MMP-8 Protein, His Tag (MM8-M52H7) is expressed from human 293 cells (HEK293). It contains AA Phe 21 - Gly 262 (Accession # O70138-1).
Species Reactivity：Mouse
Host：HEK293
Tag：C-10×His
Exp Region：Phe 21 - Gly 262
Format：Liquid
Conjugate：Unconjugated
Swiss-Prot：O70138-1
Endotoxin：1.0 EU per μg
Purity：90%
Buffer：25 mM MES, 150 mM NaCl, 20% Glycerol, pH 5.5, 0.05% Brij-35
