Dengue is a mosquito-borne viral disease widely spread all over the world transmitted by 4 serotypes of dengue virus (DENV).
The symptoms range from mild dengue fever to dengue hemorrhagic fever (DHF) and dengue shock syndrome (DSS) with high mortality.
Currently, most of the studies on DENV vaccines emphasize on its envelope protein which is essential for viral attachment and fusion (i.e., Sanofi’s tetravalent dengue vaccine Dengvaxia).
However, the vaccine of envelope protein still needs to be improved to maximize its efficiency on people never infected with DENV before, which requires more research to be conducted on the DENV envelope protein.
特徴
This protein carries a polyhistidine tag at the N-terminus.
The protein has a calculated MW of 46.2 kDa.
The protein migrates as 55-60 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
仕様
容量：50ug
Source：DENV2 (strain Thailand/16681/1984) Envelope Protein, His Tag (ENN-D5244) is expressed from human 293 cells (HEK293). It contains AA Met 281 - Ser 677 (Accession # P29990).
