Natural cytotoxicity triggering receptor 1 (NCR1) is also known as Natural killer cell p46-related protein (NK-p46), Lymphocyte antigen 94 homolog (LY94), CD antigen CD335, which belongs to the natural cytotoxicity receptor (NCR) family.
NCR1 contains two Ig-like (immunoglobulin-like) domains.
NCR1 interacts with CD247 and FCER1G.
NCR1 / CD335 may contribute to the increased efficiency of activated natural killer (NK) cells to mediate tumor cell lysis.
特徴
This protein carries a human IgG1 Fc tag at the C-terminus.
The protein has a calculated MW of 36.4 kDa.
The protein migrates as 40-43 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
仕様
容量:100ug
Source:Human NKp46 Protein, Fc Tag (NC1-H5258) is expressed from human 293 cells (HEK293). It contains AA Glu 34 - Thr 118 (Accession # O76036-1).
Species Reactivity:Human
Host:HEK293
Tag:C-Fc
Exp Region:Glu 34 - Thr 118
Format:Powder
Conjugate:Unconjugated
Swiss-Prot:O76036-1
Endotoxin:1.0 EU per μg
Purity:90%
Buffer:50 mM Tris, 100 mM Glycine, 25 mM Arginine, 150 mM NaCl, pH7.5