The herpes simplex virus type 1 (HSV-1) gH-gL complex which is found in the virion envelope is essential for virus infectivity and is a major antigen for the host immune system.The heterodimer glycoprotein H-glycoprotein L is required for the fusion of viral and plasma membranes leading to virus entry into the host cell.
Following initial binding to host receptor, membrane fusion is mediated by the fusion machinery composed of gB and the heterodimer gH/gL.
May also be involved in the fusion between the virion envelope and the outer nuclear membrane during virion morphogenesis.
特徴
This protein carries a twin strep tag at the C-terminus.
The protein has a calculated MW of 87.2 kDa & 24.9 kDa.
The protein migrates as 35 kDa and 95-110 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
仕様
容量：50ug
Source：HSV-1 (strain 17) gH&gL Protein, Twin-Strep Tag&His Tag (GHL-H5283) is expressed from human 293 cells (HEK293). It contains AA Gln 19- Ala 792 & Gly 20- Leu 224 (Accession # P06477 & P10185).
