TGF type I receptor also called the activin receptor-like kinase 5 (ALK5) and involved in TGF signaling.
TGFβ signaling is mediated by the interaction of TGFβ ligands (TGFβ 1, 2 or 3) with cell surface receptors, the TGF type I, type II and type III receptors.
Signaling is initiated by binding of TGF to the TGF type II receptor forming a ligand-receptor complex which interacts with the TGF type I receptor.
特徴
This protein carries a human IgG1 Fc tag at the C-terminus.
The protein has a calculated MW of 36.7 kDa.
The protein migrates as 43-48 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
仕様
容量：100ug
Source：Human TGF-beta RI Protein, Fc Tag (TG1-H5254) is expressed from human 293 cells (HEK293). It contains AA Leu 34 - Leu 126 (Accession # P36897-1).
