Human coronavirus NL63 (HCoV-NL63) is one of seven known coronaviruses to infect humans.
The virus is an enveloped, positive-sense, single-stranded RNA virus which enters its host cell by binding to ACE2.
Infection with the virus has been confirmed worldwide, and has an association with many common symptoms and diseases.
The spike protein of HCoV-NL63 is a trimer protruding from the viral membrane to engage cellular receptors and mediate viral fusion with host membranes.
Each spike trimer contains two large regions: N-terminal S1 responsible for receptor binding and C-terminal S2 responsible for fusion.
特徴
This protein carries a polyhistidine tag at the C-terminus, followed by an Avi tag (Avitag).
The protein has a calculated MW of 148.6 kDa.
The protein migrates as 200-250 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
仕様
容量：200ug
Source：Biotinylated HCoV-NL63 Spike Trimer Protein, His,Avitag (SPN-H82E7) is expressed from human 293 cells (HEK293). It contains AA Phe 16 - Asn 1291 (Accession # Q6Q1S2-1).
