Interleukin-27 receptor subunit alpha ( IL27RA) is also known as Cytokine receptor WSX-1, Cytokine receptor-like 1, Type I T-cell cytokine receptor (TCCR), ZcytoR1, IL27RA belongs to the type I cytokine receptor family and type 2 subfamily.
IL27RA contains three fibronectin type-III domains.
IL27RA is highly expressed in lymphoid tissues such as spleen, lymph nodes and peripheral blood leukocytes.
IL27RA is receptor for IL27, but requires IL6ST/gp130 to mediate signal transduction in response to IL27.
IL27RA involved in the regulation of Th1-type immune responses.
IL27RA also appears to be involved in innate defense mechanisms.
特徴
This protein carries a polyhistidine tag at the C-terminus.
The protein has a calculated MW of 54.2 kDa.
The protein migrates as 70-85 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
仕様
容量:1mg
Source:Human IL-27 Ra Protein, His Tag (ILA-H52Hb) is expressed from human 293 cells (HEK293). It contains AA Gln 33 - Arg 514 (Accession # AAH28003.1).