T-cell surface glycoprotein CD3 delta & CD3 gamma chain, also known as CD3D & CD3G or CD3D&CD3G respectively, are single-pass type I membrane proteins.
CD3D, together with CD3- epsilon(CD3E) , CD3-gamma and CD3-zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T cell receptor-CD3 complex.
T cell receptor-CD3 complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways.
特徴
Marmoset CD3E&CD3G Heterodimer Protein, Fc Tag&Fc Tag is produced by co-expression of CD3E and CD3G, has a calculated MW of 37.4 kDa (CD3E) & 36.4 kDa (CD3G).
Subunit CD3E is fused with a human IgG1 Fc tag at the C-terminus and subunit CD3G is fused with a human IgG1 Fc tag at the C-terminus.
The reducing (R) heterodimer protein migrates as 41-50 kDa when calibrated against Star Ribbon Pre-stained Protein Marker due to glycosylation.
仕様
容量:1mg
Source:Marmoset CD3E&CD3G Heterodimer Protein, Fc Tag&Fc Tag (CDG-M5253) is expressed from human 293 cells (HEK293). It contains AA Gln 22 - Asp 117 (CD3E) & Gln 51 - Ser 139 (CD3G) (Accession # Q3LRP4-1 (CD3E) & A0A2R8MU93-1 (CD3G)).
Species Reactivity:Marmoset
Host:HEK293
Tag:C-Fc | C-Fc
Exp Region:Gln 22 - Asp 117 (CD3E) & Gln 51 - Ser 139 (CD3G)