The receptor systems for IL6, LIF, OSM, CNTF, IL11 and CT1 can utilize IL6ST for initiating signal transmission.
The IL11/IL11RA/IL6ST complex may be involved in the control of proliferation and/or differentiation of skeletogenic progenitor or other mesenchymal cells (Probable).
Essential for the normal development of craniofacial bones and teeth.
Restricts suture fusion and tooth number.Soluble form of IL11 receptor (sIL11RA) that acts as an agonist of IL11 activity.
The IL11:sIL11RA complex binds to IL6ST/gp130 on cell surfaces and induces signaling also on cells that do not express membrane-bound IL11RA in a process called IL11 trans-signaling.
特徴
This protein carries an Avi tag (Avitag) at the C-terminus.
The protein has a calculated MW of 39.8 kDa.
The protein migrates as 50 kDa and 55 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
仕様
容量：200ug
Source：Biotinylated Mouse IL-11 R alpha Protein, Avitag (ILR-M82E8) is expressed from human 293 cells (HEK293). It contains AA Cys 26 - Gln 367 (Accession # Q64385-1).
