Urokinase plasminogen activator surface receptor (U-PAR) is also known as PLAUR, Monocyte activation antigen Mo3, CD antigen CD87.
PLAUR contains three UPAR/Ly6 domains.
U-PAR is expressed in neurons of the rolandic area of the brain (at protein level) and is also expressed in the brain.
PLAUR / CD87 interacts with MRC2, SRPX2 and SORL1.
PLAUR / UPAR acts as a receptor for urokinase plasminogen activator and plays a role in localizing and promoting plasmin formation.
U-PAR mediates the proteolysis-independent signal transduction activation effects of U-PA.
特徴
This protein carries a polyhistidine tag at the C-terminus.
The protein has a calculated MW of 35.0 kDa.
仕様
容量:200tests
Source:APC-Labeled Human uPAR Protein, His Tag (UPR-HA2H9) is produced via conjugation of APC to Human uPAR Protein, His Tag with a new generation site-specific technology under optimal conditions with a proprietary technology. Human uPAR Protein, His Tag is expressed from human 293 cells (HEK293). It contains AA Leu 23 - Arg 303 (Accession # Q03405-1).