Laminin-α2 is a critical component of the laminin heterotrimer, which along with laminin-β1 or β2 and laminin-γ1 form the structural glycoproteins laminin-211 and laminin-221 in skeletal muscle.
Laminin-211 is the most abundant laminin isoform in the basement membrane of adult skeletal muscle.
Laminin-211 and -221 polymerize with each other and interact with nidogen and collagen-IV to form the muscle basal lamina.
Laminin-211 and laminin-221 bind to muscle cell surface through the α7β1 integrin and α-dystroglycan of the dystrophin glycoprotein complex via their globular C-terminal domains.
特徴
This protein .
仕様
容量：100ug
Source：Human Laminin 211 Protein, premium grade (LA8-H5263) is expressed from human 293 cells (HEK293).
