This gene encodes a member of the semaphorin family of proteins.
The encoded preproprotein is proteolytically processed to generate the mature glycosylphosphatidylinositol (GPI)-anchored membrane glycoprotein.
The encoded protein is found on activated lymphocytes and erythrocytes and may be involved in immunomodulatory and neuronal processes.
The encoded protein carries the John Milton Hagen (JMH) blood group antigens.
Mutations in this gene may be associated with reduced bone mineral density (BMD).
Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.
特徴
This protein carries a polyhistidine tag at the C-terminus, followed by an Avi tag (Avitag).
The protein has a calculated MW of 72.0 kDa.
The protein migrates as 70-75 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
仕様
容量：200ug
Source：Biotinylated Human Semaphorin 7A Protein, His,Avitag (SEA-H82E7) is expressed from human 293 cells (HEK293). It contains AA Gln 45 - Ala 648 (Accession # O75326-1).
