Lymphocyte activation gene 3 protein (LAG3) is also known as CD antigen CD223 and protein FDC, which belongs to immunoglobulin (Ig) superfamily and contains 4 extracellular Ig-like domains.
The LAG3 gene contains 8 exons.
The sequence data, exon/intron organization, and chromosomal localization all indicate a close relationship of LAG3 to CD4.
LAG3 /CD223 involved in lymphocyte activation.
LAG3 /CD223 binds to HLA class-II antigens.
特徴
This protein carries a human IgG1 Fc tag at the C-terminus.
The protein has a calculated MW of 71.7 kDa.
The protein migrates as 80-100 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
仕様
容量：100ug
Source：Mouse LAG-3 Protein, Fc Tag (LA3-M5253) is expressed from human 293 cells (HEK293). It contains AA Gly 24 - Leu 442 (Accession # Q61790-1).
