Wnt surrogate is a Wnt pathway agonists and related compositions, which may be used in any of a variety of therapeutic methods for the treatment of diseases.
特徴
This protein carries a human IgG1 Fc tag at the C-terminus.
The protein has a calculated MW of 58.5 kDa.
The protein migrates as 65-75 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
仕様
容量:1mg
Source:Recombinant Human Wnt3a Surrogate Protein is a engineered Wnt Surrogate Protein and is produced from human 293 cells (HEK293). It consists of the LRP-binding domain of DKK fused to a specific, high affinity binder of Frizzled receptors.Recombinant Human Wnt3a Surrogate Protein activates Wnt signaling pathways and is necessary for cell proliferation and differentiation and the self-renewal of stem cells. It is widely used for supporting organoid culture, including intestinal, stomach, liver, lung organoids.