83-3889-29　Biotinylated Human HLA-A*11：01＆B2M＆EBV （AVFDRKSDAK） Complex Protein （Monomer, MALS verified） 200ug　HLE-H82E5-200ug

特徴

• 背景
• Epstein-Bar Virus (EBV), also known as human herpesvirus 4, belongs to gamma herpes virus family and is a very common human virus worldwide.
• EBV causes infectious mononucleosis (IM) and also associates to some specific types of cancers such as Burkitt’s lymphoma (BL) and gastric carcinoma (GC).
• Glycoprotein B (gB) plays an important role in viral entry by binding with αvβ6/αvβ8 integrins to trigger the membrane fusion and entry process of epithelial cells, which makes it become an great target for EBV research.
• Epstein-Bar Virus (EBV), also known as human herpesvirus 4, belongs to gamma herpes virus family and is a very common human virus worldwide.
• EBV causes infectious mononucleosis (IM) and also associates to some specific types of cancers such as Burkitt’s lymphoma (BL) and gastric carcinoma (GC).
• Glycoprotein B (gB) plays an important role in viral entry by binding with αvβ6/αvβ8 integrins to trigger the membrane fusion and entry process of epithelial cells, which makes it become an great target for EBV research.
• The Human HLA-A*1101 EBV (AVFDRKSDAK) complex protein is a complex of HLA-A*1101 of the MHC Class I, B2M and AVFDRKSDAK peptide of the EBV.
• 特徴
• Biotinylated Human HLA-A*11:01&B2M&EBV (AVFDRKSDAK) Complex Protein is produced by co-expression of HLA and B2M loaded with EBV peptide.This protein carries a polyhistidine tag at the C-terminus, followed by an Avi tag (Avitag).The protein has a calculated MW of 36.0 kDa and 11.7 kDa.
• The protein migrates as 38-43 kDa and 12 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.