83-3889-01 Human CD39L1 / ENTPD2 Protein, His Tag （active enzyme, MALS verified） 500ug CD1-H53H3-500ug
特徴
- 背景
- CD39L1, also known as ENTPD2 and NTPDase2, is an ectonucleotidase belonging to the CD39 family.
- It is found on the surface of vascular adventitial cells and accessory vascular cells .
- CD39L1 is a Ca2+ and Mg2+ dependent enzyme that hydrolyze ATP and other nucleotides to regulate purinergic neurotransmission.
- Hydrolyzes ADP only to a marginal extent.
- The order of activity with different substrates is ATP > GTP > CTP = ITP > UTP >> ADP = UDP.
- CD39L1 plays a role in regulating thrombosis and inflammation .
- It is considered to be a therapeutic target for thromboregulation and the treatment of vascular inflammation.
- 特徴
- This protein carries a polyhistidine tag at the C-terminus.
- The protein has a calculated MW of 49.0 kDa.
- The protein migrates as 36-37 kDa and 57-63 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
仕様
- 容量：500ug
- Source：Human CD39L1/ENTPD2 Protein, His Tag (CD1-H53H3) is expressed from CHO cells. It contains AA Thr 29 - Asp 460 (Accession # Q9Y5L3-1).
- Species Reactivity：Human
- Host：CHO
- Tag：C-10×His
- Exp Region：Thr 29 - Asp 460
- Format：Liquid
- Conjugate：Unconjugated
- Swiss-Prot：Q9Y5L3-1
- Endotoxin：1.0 EU per μg
- Purity：95%
- Buffer：20 mM Tris, 150 mM NaCl, pH7.5
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