The epidermal growth factor receptor (EGFR; ErbB-1; HER1 in humans) is the cell-surface receptor for members of the epidermal growth factor family (EGF-family) of extracellular protein ligands.
The epidermal growth factor receptor is a member of the ErbB family of receptors, a subfamily of four closely related receptor tyrosine kinases: EGFR (ErbB-1), HER2/c-neu (ErbB-2), Her 3 (ErbB-3) and Her 4 (ErbB-4).
Mutations affecting EGFR expression or activity could result in cancer.
特徴
This protein carries a human IgG1 Fc tag at the C-terminus.
The protein has a calculated MW of 95.7 kDa.
The protein migrates as 110-130 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
仕様
容量：100ug
Source：Mouse EGF R Protein, Fc Tag (EGR-M5257) is expressed from human 293 cells (HEK293). It contains AA Leu 25 - Ser 647 (Accession # Q01279-1).
Species Reactivity：Mouse
Host：HEK293
Tag：C-Fc
Exp Region：Leu 25 - Ser 647
Format：Powder
Conjugate：Unconjugated
Swiss-Prot：Q01279-1
Endotoxin：1.0 EU per μg
Purity：95%
Buffer：50 mM Tris, 100 mM Glycine, 25 mM Arginine, 150 mM NaCl, pH7.5
