This gene encodes a member of the glycosyl hydrolase 35 family of proteins.
Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature lysosomal enzyme.
This enzyme catalyzes the hydrolysis of a terminal beta-linked galactose residue from ganglioside substrates and other glycoconjugates.
Mutations in this gene may result in GM1-gangliosidosis and Morquio B syndrome.
[provided by RefSeq, Nov 2015]
特徴
This protein carries a polyhistidine tag at the C-terminus.
The protein has a calculated MW of 75.5 kDa.
The protein migrates as 80-95 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
仕様
容量：1mg
Source：Human beta-Galactosidase-1 Protein, His Tag (BG1-H52H3) is expressed from human 293 cells (HEK293). It contains AA Leu 24 - Val 677 (Accession # P16278-1).
Species Reactivity：Human
Host：HEK293
Tag：C-10×His
Exp Region：Leu 24 - Val 677
Format：Liquid
Conjugate：Unconjugated
Swiss-Prot：P16278-1
Endotoxin：1.0 EU per μg
Purity：95%
Buffer：50 mM Tris, 150 mM NaCl, 20% Glycerol, pH7.5
