HLA-A, B, and C are transmembrane glycoproteins in the major histocompatibility complex 1 (MHC I) family.
The C receptor is a heterodimer consisting of a HLA-C mature gene product (heavy chain) and β2-microglobulin (light chain).
The mature C chain is anchored in the membrane.
HLA class I molecules play a central role in the immune system by presenting peptides derived from endoplasmic reticulum lumen.
HLA-C are expressed in nearly all cells, and present small peptides to the immune system which surveys for non-self peptides.
特徴
This protein carries a polyhistidine tag at the C-terminus, followed by an Avi tag (Avitag).
The protein has a calculated MW of 36.1 kDa and 11.7 kDa.
The protein migrates as 40-43 kDa and 10 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
仕様
容量：200ug
Source：Biotinylated Human HLA-C*07:02:01&B2M Monomer Protein (HLM-H82Ed) is expressed from human 293 cells (HEK293). It contains AA Cys 25 - Ile 308 (HLA-C*07:02:01) & Ile 21 - Met 119 (B2M) (Accession # P10321-1 (HLA-C*07:02:01) & P61769-1 (B2M)).
Species Reactivity：Human
Host：HEK293
Tag：C-10×His & C-Avi
Exp Region：Cys 25 - Ile 308 (HLA-C*07:02:01) & Ile 21 - Met 119 (B2M)
