Integrin alpha-1/beta-1 is a receptor for laminin and collagen.
The Integrin alpha-1/beta-1 and Integrin alpha-2/beta-1 integrins provide critical support for vascular endothelial growth factor signaling, endothelial cell migration, and tumor angiogenesis.
It recognizes the proline-hydroxylated sequence G-F-P-G-E-R in collagen.
Involved in anchorage-dependent, negative regulation of EGF-stimulated cell growth.
特徴
Human/Mouse ITGA1&ITGB1 Heterodimer Protein, His Tag&Tag Free, produced by co-expression of ITGA1 and ITGB1, has a calculated MW of 130.0 kDa & 83.5 kDa.
The protein migrates as 100-115 kDa and >180 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under non-reducing (NR) condition (SDS-PAGE) due to glycosylation.
仕様
容量：1mg
Source：Human/Mouse ITGA1&ITGB1 Protein, His Tag&Tag Free (IN1-H52W9) is expressed from human 293 cells (HEK293). It contains AA Phe 29 - Pro1141 & Gln 21 - Asp 728 (Accession # P56199-1 & P09055-1).
